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what are wrinkles?

Wrinkles are creases, folds or ridges in the skin. Wrinkles are mostly caused by facial movements and expression, but can also be caused by sun damage, smoking, dehydration and environmental and genetical factors. Wrinkles tend to appear at parts which receive the most sun exposure, like the face and neck, the back of the hands and the arms.


Prior to the treatment, we always provide a free initial consultation in which we discuss the various treatment methods and you meet your consultant and the doctor. We discuss the potential treatment method(s), your wishes, and your expectations. According to the principle of the ‘whole face approach’, we create a treatment plan together with you. During the initial consultation, we also ask about your medical history, previous treatments, and any use of medication in order to eliminate all potential risks and treat you in a safe way.

Every wrinkle has its own story. Therefore, we perform a detailed analysis of the cause of your wrinkles. We do this based on our Magic Markers Method and, if necessary, a 3D photo in which you, after editing by the doctor, can see the treatment results in advance.


price list

Botox Price
 1 zone (light/normal)  € 160/220,-
 2 zones (light/normal)  € 300/350,-
 3 zones  € 440,-
 Botox (whole face)  € 600,-


Fillers Price
Juvéderm Voluma – Juvéderm Volift – Juvéderm Volbella – Juvéderm Volight Juvéderm 1ml  € 500,-
Juvéderm 2ml  € 850,-

What causes wrinkles to appear?

Skin loses some of its flexibility with age. This causes wrinkles to remain visible and become deeper. In addition, aging is associated with significant loss of volume. This also causes wrinkles to appear. The main reason for this is the decline of the proteins: collagen and elastin. Connective tissue exists for the biggest part of collagen. Elastin ensures the skin’s suppleness. Due to the decline of collagen and elastin wrinkles will occur. Wrinkles can be classified in fine lines and deep wrinkles. Fine lines occur due to elastin decrease. These fine lines disappear when you lightly squeeze the skin. Deep wrinkles are ridges in the skin. These wrinkles are caused by tightening of the muscles. With Botox and/or hyaluronic acid, we can fill up wrinkles and correct the volume that is deficit.

Wrinkles are caused by:

  • Natural aging, enhanced by, for example, stress or smoking
  • Hormonal aging, as seen when getting older
  • Facial movements and expressions
  • UV radiation, due to sunlight exposure

how to get rid of wrinkles?

The removal of wrinkles depends on the type of wrinkle. Sometimes fine wrinkles can be reduced by good skincare. If the wrinkles are deeper, then different treatments are possible. For the treatment of fine lines, we often use injectables as Botox. Deep wrinkles that we can’t reduce well with Botox, we treat with fillers.

Best treatment for wrinkles

Wrinkles can be effectively treated using two methods: Botox and/or fillers. It depends on the depth of your wrinkles which treatment’s the best treatment for your wrinkles. During the initial consultation at Kliniek Dokter Frodo, we perform a thorough analysis of your face. Based on this, we will choose the treatment for wrinkles that will best suits you. A wrinkles treatment, including consultation, usually takes about 30 minutes. The exact duration depends on the choice of treatment made in consultation.

Botoxwrinkles treatment

Prior to the treatment, you will receive a detailed consultation with your doctor. The treatment with Botox itself takes no more than 5 minutes. The botulinum toxin is injected directly into the muscle via a thin needle. After the treatment, there may be slight redness or a light swelling. This fades very quickly, often within 10 minutes. You can resume your daily activities right after the treatment.

Filler wrinkles treatment

When filling up a volume deficit, we use a cannula and the skin – if desired – is locally sedated. The hyaluronic acid is applied just under the skin and reduced the wrinkles or causes them to disappear entirely. The recovery time is virtually zero and the results are immediately visible.

With our treatments against frown lines, crow’s feet, and forehead wrinkles, you get the best out of yourself. During the free initial consultation, we look at whether we can help you with this. Kliniek Dokter Frodo’s policy is only proceed with treatment if a number of criteria are met.

Results may vary based on a variety of factors, to ensure suitability you must attend a consultation. All our consultations are free of charge.

Overhanging eyelids

If you are suffering from overhanging eyelids (and are constantly raising your eyebrows because of it), we may recommend that you first contact a plastic surgeon for blepharoplasty.

High expectations

We sometimes choose not to treat someone because we feel we cannot meet their expectations. High expectations are great, but expectations that are too high are a good reason for us not to proceed.

You can also opt for a Liquid Facelift. This treatment is fully customized and is a combination of fillers and specialized treatment techniques. A Liquid Facelift will lead to a natural result which gives you back the volume and youthfulness you’ve lost in your face. 

Wrinkles treatment for men

With men, different features are considered beautiful than for women. That’s why we have adjusted our wrinkles treatment for men to be slightly different than those for women. In our clinic, we discuss the possibilities that apply to you specifically. According to the principle of the ‘whole face approach’, we create a treatment plan together with you in order to achieve the best results.

After the wrinkles treatment

Botox wrinkles treatment

Shortly after the treatment with Botox, the skin will look normal again. Two to four days after the Botox wrinkles treatment, you already see a small reduction in wrinkles. Before the botulinum toxin fully does its job, approximately two weeks have passed. After two weeks, the maximum effect is reached and you return to the clinic for a check-up. The skin looks relaxed and the wrinkle becomes less deep. The effect lasts for three to six months. For the best results, the treatment is sometimes complemented or combined with other treatments, such as fillers and/or carboxytherapy.

Filler wrinkles treatment

With the filler treatment, you will see immediate results after the wrinkles treatment. However, there may be some swelling on the first day. The swelling is worst on the first days and disappears within a few days. Sometimes, there is a bruise that can be visible for one to two weeks. In this case, avoid direct sunlight to prevent pigmentation.

The hyaluronic acid needs two weeks to properly settle into the surrounding tissue. After two weeks, you come back for a check-up. You always need to return for a check-up. The hyaluronic acid needs a few days to settle. During the first week after the treatment, the filler can shift somewhat and look irregular. We can correct this during the check-up. The hyaluronic acid is broken down after 1,5 years at the earliest. For most people, this takes longer. We recommend not waiting until the results are completely gone, but returning before everything disappears. This prevents a yo-yo effect.

Is there something I can do against wrinkles?

Absolutely, next to getting a Botox wrinkles treatment or a filler wrinkles treatment the following steps will get you a long way:

  • Good skincare
  • Microneedling
  • Sufficient sleep
  • Sufficient drinking water and/or green tea
  • Eating lots of vegetables and fruit with antioxidants


Is the treatment painful?

We can administer a topical anaesthetic to minimise any discomfort. Most clients report little or no pain during treatment.

How long does the treatment take?

Appointment times vary, depending on the desired effect, and you must attend a consultation. As a rough guide, the treatment can take around 30 minutes.

Is it safe?

Botox wrinkles treatment

Botox has been used in medicine safely and without any serious side effects for almost forty years. In very rare cases, when too much is used, a tight feeling can occur that lasts 1 to 2 months. However, this only happens sporadically.

Filler wrinkles treatment

Hyaluronic acid (Juvéderm or Restylane) is an endogenous substance, which means it is very safe. The body virtually does not react to it. An allergic reaction is very unlikely, and if necessary, the filler is soluble. This makes it a very suitable and safe product.

What’s the minimum age to undergo a wrinkles treatment?

If you are younger than 18 years old, you cannot undergo cosmetic treatment at our clinic.

Will I receive guidance?

If you are afraid of needles and would still like to undergo treatment, we will provide additional guidance and ensure that you feel completely at ease. With the right tools, we can get you through the treatment without experiencing pain or distress.

How long will the results last?

The result of the Botox treatment remains visible for 3 to 4 months. The result of the filler treatment remains visible for 6 to 18 months. There are great individual differences, and usually, it says in much longer. The aging of the face continues slowly (it loses more volume), which can cause the result to decline somewhat. At this point, the filler is still present, but preservering the result with a touch-up treatment is desirable. We recommend not waiting until the result is completely gone, but coming back before everything disappears, this avoiding a yo-yo effect. We use smaller quantities during a touch-up treatment.

What if I am not satisfied?

Should you unfortunately be unsatisfied with the results, then we can easily dissolve the hyaluronic acid without any residual symptoms.


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